CO poisoning: clinical features

Clinical - Respiratory/Pulmonary

Issue : Desiccated (or dry) CO2 absorbers such as soda lime and Baralyme can degrade inhaled anesthetics to carbon monoxide, and my produce carboxyhemoglobin concentrations in excess of 30%.

Incidence : The incidence of CO exposure is 0.46% for the first case of the day (2.9% in non-OR settings) and overall incidence is 0.26%.

Factors that increase the production of CO and carboxyhemoglobin:

1.    Inhaled anesthetic used: des>/=enflurane>iso>>halothane=sevo

2.    Absorbent dryness

3.    Type of absorbent (Baralyme>soda lime)

4.    Increased temperature

5.    Low fresh gas flow

6.    Increasing anesthetic concentration

7.    Size of patient compared to amount of absorbent (i.e. more absorbent and hence more CO exposure per unit of patient mass

Interventions to reduce the risk of CO exposure:

1.    Educate personnel on risk of CO production

2.    Turn off anesthesia machine at the end of the day (leaving the anesthesia machine on at high oxygen flow rates overnight can dry the soda lyme)

3.    Change CO2 absorber if you find gas flowing in machine

4.    Rehydrate desiccated absorbers

5.    Use absorbers that do not contain strong bases

Sources

    Anaesthesia;2006 May;61(5):462-8

    [PubMed: 16674622]

    See also CO poisoning

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Answered correctly

2008

Year asked