Advanced, Clinical - Neurologic, Clinical - Neuromuscular Diseases and Disorders, Organ-Based and Clinical Sciences
Rare autoimmune disorder, causes peripheral muscle weakness. Antibodies are directed against calcium channels at the neuromuscular junction. Frequently a complication of malignancy (most commonly small cell lung ca). Cancer treatment relieves symptoms. Strength increases with increased use. May have autonomic abnormalities (gastroparesis, orthostatic hypotension or urinary retention).