Electrolyte Homeostasis: hormones

Clinical - Endocrine/Metabolic, Clinical - Renal/Urine/Electrolytes

Sodium levels are affected by ADH (hypothalamus), aldosterone (renin-angiotensin-aldosterone axis), glucocorticoids and mineralocorticoids (pituitary axis). Potassium is affected by aldosterone, steroids, and insulin . Calcium levels are increased as PTH is released.

Electrolytes and Related Hormones

  • Sodium: ADH (retains fluid), glucocorticoids (cortisol) and mineralocorticoids (aldosterone) both retain Na
  • Potassium: aldosterone (excretes K), gluco- and mineralocorticoids (excrete K), beta-adrenergic agonists (decrease K), insulin (decreases serum K)
  • Calcium: PTH (increases Ca++)


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