Hypoxic pulmonary vasodilation

Physiology - Respiratory

For information on Hypoxic Pulmonic Vasoconstriction , see [Hypoxic Pulmonary Vasoconstriction]https://www.openanesthesia.org/Hypoxic_Pulmonary_Vasoconstriction "Hypoxic Pulmonary Vasoconstriction"

While [Hypoxic Pulmonary Vasoconstriction]https://www.openanesthesia.org/Hypoxic_Pulmonary_Vasoconstriction "Hypoxic Pulmonary Vasoconstriction") is a well-described phenomena, mammalian lungs may be capable of vasodilating following a hypoxemic challenge (pO2 < 25 mm Hg . It is thought that this response is mediated by adenosine.  This effect is well described in sea lions, in which case it is mediated by hydrogen sulfide.

Sources

    Am J Physiol;1984 Oct;247(4 Pt 2):H541-7

    [PubMed: 6437241]

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2008

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