Long QT syndrome: Medications

Advanced, Basic Sciences, Pharmacology

The QT interval is normally < 450 ms in males, < 470 ms in females.

Prolongation is associated with a risk of the arrhythmia torsades de pointea (TdP), a potentially life threatening ventricular arrhythmia, when drugs that further prolong the QT are administered. Examples of these drug classes are include:

  1. Antiarrhythmics: Amiodarone, Satalol, Quinidine, Procainamide
  2. Antibiotics: Ciprofloxacin, Levofloxacin, Moxifloxacin, Erythromycin, Ketoconazole
  3. Antidepressants: Amitriptyline, Imipramine, Desipramine, Fluoxetine, Sertaline
  4. Antipsychotics: Droperidol, Haloperidol, Thioridazine
  5. Others: Dolasetron, Zofran, Methadone, all the halogenated anesthetics

97%

Answered correctly

2018

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96%

Answered correctly

2013

Year asked