TAVI complications

Clinical - Cardiovascular

Transcatheter aortic valve implantation is becoming a popular option for patients with severe aortic stenosis who are poor surgical candidates.  The procedure is less invasive than open aortic valve replacement; however, perioperative complications from this procedure can be serious and life-threatening.  Vascular access is usually obtained via the common femoral artery; the prosthetic valve must travel from this entry point to the heart, and then the valve must be deployed in a manner that disables native valve function.

Complications from valve positioning and deployment include atrioventricular block requiring pacemaker implantation (incidence 15.7%) , prosthesis dislocation/embolization, retrograde embolization, acute coronary obstruction, paravalvular regurgitation, pericardial tamponade, TIA/stroke, acute renal failure requiring renal replacement therapy, and prosthesis-related endocarditis.

Acute ST changes observed on EKG and or LV dysfunction observed on TEE immediately after deployment of the valve suggest acute coronary occlusion. This complication can be managed by percutaneous coronary intervention and stent placement. “Reported cases of coronary obstruction after TAVI occurred more frequently in women, in patients receiving a balloon-expandable valve, and the LCA was the most commonly involved artery. Percutaneous coronary intervention was a feasible and successful treatment in most cases.”


    Expert Rev Cardiovasc Ther;2011 Jul;9(7):913-26

    [PubMed: 21809973]

    JACC Cardiovasc Interv;2013 May;6(5):452-61

    [PubMed: 23602458]


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